2012年6月2日 星期六

Staging AIDS Complicated With Lymphoma


Diagnosing AIDS-related lymphoma is generally done quite late, after the disease has already advanced. In order to see whether the disease has spread within the lymph system or to other organs, doctors need to perform a procedure called staging that will finally determine the evolution stage of the disease. Knowing all these facts, the doctor can advice the patient what treatment to follow.

One of the tests made to determine the stage of the lymphoma is the CT (computer tomography) an X-ray based machine that will show detailed image of your organs and other related structures to them. You could be advised to take some oral drugs or the doctors will give you an injection that contains some dye, which will help them see a clearer image of your lymph system and bloodstream.

Another test is the PET scan which is designed to find the malign tumors inside your body. The substance used to track the tumors is a radionuclide glucose injected in your vein. This substance will brighten the tumor in the picture because the tumor uses the glucose for its development.

MRI (magnetic resonance imaging) is also useful because it takes detailed pictures of your body, using magnet, radio waves. In this case, the substance used to brighten tumors in the picture is gadolinium.

Other reliable tests are the bone marrow biopsy, made on the hipbone or breastbone, and the lumbar puncture that takes some drops of the cerebrospinal fluid from the spinal column which will be analyzed in the laboratory to see if there are any signs of cancer.

AIDS-related lymphoma stages might include the E and S stages.

The E stage stands for extra-nodal meaning that the cancer has not reached the lymph nodes yet and that it is situated in other organs.

The S stage means that the cancer has reached the spleen and affects it.

Stage I of AIDS-related lymphoma is classified as stage I and stage IE; stage I means that the cancer has affected one group of lymph nodes; stage IE means that the cancer has not reached the lymph nodes yet and affects other organs.

Stage II is classified as stage II (cancer has affected two or more lymph node groups on the same side of the diaphragm) and stage IIE (cancer has affected the lymph nodes near the previous affected organs).

Stage III is divided into stage III, stage IIIE, stage IIIS and stage IIIE+S

Stage III - cancer has affected lymph nodes on the both sides of the diaphragm.

Stage IIIE - besides the lymph node group on the both sides of the diaphragm, cancer is found in other organs too.

Stage IIIS - besides the lymph node group on the both sides of the diaphragm, cancer is found in the spleen too.

Stage IIIE+S - besides the lymph node group on the both sides of the diaphragm, cancer is found in other organs and in the spleen too.

In stage IV the cancer is considered to have attacked multiple organs and associated lymph nodes and also distant lymph node groups.

In AIDS-related lymphoma patients the risk that the cancer will spread towards CNS (central nervous system) is quite high.

In treating the disease, the lymphoma is grouped based on where the cancer started in the organism: if it starts from the lymph nodes is called peripheral lymphoma; if it starts is the CNS is called primary CNS lymphoma.




So, if you want to find out more about non hodgkins lymphoma or even about mantle cell lymphoma please visit this link http://www.lymphoma-center.com





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2012年6月1日 星期五

Appropriate Treatment - Non-Hodgkin's Lymphoma's Cure?


How can cancer be treated? This is the most frequent question in medical research. New treatments are tested on patients under close observation of medical squads. It's a hard work for researchers who have to determine an optimal dose of the treatment for each patient, to guarantee them the lack of side effects but especially a chance of survival.

Researchers also talk about a breast cancer study that proved the beneficial effect of chemotherapy tested right after a surgical intervention. Positive results encouraged researchers to move on to another type of cancer, non-Hodgkin's lymphoma, believing that appropriate treatment and observation can lead to a possible curing.

Non-Hodgkin's lymphoma, meaning cancers of lymph glands, occurs around the older people, about the age of 60, but it can be discovered at almost any age. It's one of the most common types of lymphoma, the number of cases increasing from a year to another.

Chemotherapy could mean a chance for staying alive because its drugs have a faster and more active effect over rapidly growing cells.

The treatment for non-Hodgkin's lymphoma can be different from a patient to another depending especially on the stage of the disease. In early stages chemotherapy and radiation therapy could be enough for a fast curing. This can't be told for the most of the patients who need special treatment and attentively observation for at least four months.

Curing this type of cancer is not the biggest problem. The real problem is treatment that in most of the cases is delayed. This fact can compromise patient's health and survival chances.

Non-Hodgkin's lymphoma under-treatment is found at old patients, patients with high stage of disease, or underfed patients who often reduce medication or skip treatment.

Inappropriate treatment for non-Hodgkin's lymphoma is surely caused by the possible side-effects that can result during chemotherapy, or drug administration. Therefore, initial, the dose is reduced and after a good observation the treatment is changed for the patients who tolerate it.

Reducing treatment could mean as well for patients suffering from non-Hodgkin's lymphoma a comeback of the disease in a few years or even months.

An appropriate treatment is needed in every single case despite the age of the patient or his stage of disease, more than that these patients need a higher attention, a closer observation to lead to an optimal treatment.

Supportive care is what non-Hodgkin's lymphoma patients need to go through the full program without treatment delay or without dose reduction.

Optimizing the treatment should be the first thing for a doctor to have in mind when it comes to a non-Hodgkin's lymphoma patient and it should be a no side effects selection.




For more resources about lymphoma or even about mantle cell lymphoma please review this page http://www.lymphoma-center.com/mantle-cell-lymphoma.htm





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Different Treatments to Treat Mantle Cell Lymphoma


Lymphoma is a serious affection which affects different parts of the body and usually occurs in many forms. One of the most severe form of lymphoma is known as Mantle cell lymphoma. In addition to this, Mantle cell lymphoma is a rare form of Non-Hodgkin lymphoma which tends to develop and spread very fast to other organs of the body. Due to the fact that Mantle cell lymphoma spreads very fast to different parts of the body, treatments of this type of affection should be good enough to reach to all the infected cells. Unlike chemotherapy which is the main form of treatment, bringing successfully results, other treatments, such as surgery or radiation therapy are not enough useful to reduce the cancer.

To begin with, chemotherapy has proved to be the most efficient treatment to treat Mantle cell lymphoma. Chemotherapy can be administrated in the form of injections, drips in the veins or even tablets. Much more, a treatment for this affection may include different types of drugs and the doses depend on the patient condition. In most cases, the treatments prescribed include the CHOP regimen, a combination of four drugs which is taken in a single day and repeated every three weeks for six ot eight cycles. Even though, chemotherapy brings important results, the disease may occur again. In order to prevent a recidivism of Mantle cell lymphoma, specialists use to prescribe chemotherapy combinations, such as treatments for leukemias. On the other hand, these combinations of chemotherapy might be very toxic for some patients who suffer from Mantle cell lymphoma.

Secondly, another efficient treatment includes monoclonal antibodies such as Rituximab, usually used to treat Non-Hodgkin lymphoma and Mantle cell lymphoma as well. Another way to treat Mantle cell lymphoma which tends to be a hard procedure and not widely practiced is the bone marrow or stem-cell transplant. Radiation is another procedure which is usually used when the disease is not very severe. Much more as it is known that this disease affects many areas of the body, radiation is not the best choice.

In conclusion, even though mantle cell lymphoma tends to be an incurable disease, treatments for this affection have the role in prolonging and improving the life of the patients. Nowadays many new treatments are being tested and much more clinical trials may help the patient considerably.




So, if you want to find out more about lymphoma or even about cutaneous t cell lymphoma please visit this link http://www.lymphoma-center.com/





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Is Lymphoma Curable?


Since there are many different lymphomas, the curability of each case will vary. When lymphoma is caught in an early stage, the cure rate is higher. However, the overall cure rate for all lymphomas, in both men and women, are quite high.

Cure Rates Based On Stage Of Detection

Localized (Still in one location, has not metastasized) - Accounts for 38% of all cases; 5-year survival rate is 82.1%

Distant (Metastasis has occurred) - 45% of all lymphoma cases are of this variety. 59.9% is the 5-year survival rate.

Regional (has spread to the regional lymph nodes - 77.5% is the cure rate and this type accounts for 19 of all lymphoma cases.

Unknown (Unstaged) - 67.5% cure rate accounting for 8% of cases.

There are a plethora of types of NHL (Non-Hodgkin lymphoma) and the possibility of cure is dependent on the specific diagnosis.

Prognosis can also be different even in the same sub type of NHL.

Even in an individual who has a well-categorized case of lymphoma, the survival rate and time can be hard to guess.

Is lymphoma curable for anybody?

Cure rates depend greatly on many factors.

Thus, the answer is yes and no because it depends on what type of lymphoma one has, what lymphoma stages it may be in, the lymphoma grade, the general health of the patient, response to treatment and of course a dash of luck.

For people with quick growing lymphomas types (for example, diffuse large B cell lymphoma), the lymphoma can be potentially resolved with combination chemotherapy. However, for those individuals who respond poorly to treatment or have an early relapse, the lymphoma can be deadly in a rather short period of time. The slowly growing lymphomas are incurable with regular chemo, yet patients can live with them for years and years.

Much of deciding how to treat a specific lymphoma is based on simply observing the patient closely to see how the disease progresses so that an appropriate course of action can be prescribed.

Lymphoma Treatment

Is Lymphoma curable with chemotherapy, radiation, surgery, bone marrow transplants, etc?

Typically, one or a combination of these treatments will be used, depending upon the factors discussed above. The symptoms of lymphoma in women will vary greatly but will not necessarily provide an indication of the level of advancement of the cancer nor the potential curability of the disease. Generally speaking, lymphoma has a better than 50% cure rate and this is certainly something to be grateful for.




Tomas Schuman is a well-informed patient who writes about the Symptoms of Lymphoma in Women and attempts to provide a clear answer to the question: Is lymphoma curable?





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